The permissible exposure limit (PEL or OSHA PEL) is a legal limit in the United States for exposure of an employee to a chemical substance or physical agent such as high level noise. Permissible exposure limits are established by the Occupational Safety and Health Administration (OSHA). Most of OSHA's PELs were issued shortly after adoption of the Occupational Safety and Health (OSH) Act in 1970.

For chemicals, the chemical regulation is usually expressed in parts per million (ppm), or sometimes in milligrams per cubic meter (mg/m³). Units of measure for physical agents such as noise are specific to the agent.

A PEL is usually given as a time-weighted average (TWA), although some are short-term exposure limits (STEL) or ceiling limits. A TWA is the average exposure over a specified period, usually a nominal eight hours. This means that, for limited periods, a worker may be exposed to concentration excursions higher than the PEL, so long as the TWA is not exceeded and any applicable excursion limit is not exceeded. An excursion limit typically means that "...worker exposure levels may exceed 3 times the PEL-TWA for no more than a total of 30 minutes during a workday, and under no circumstances should they exceed 5 times the PEL-TWA, provided that the PEL-TWA is not exceeded." Excursion limits are enforced in some states (for example Oregon) and on the federal level for certain contaminants such as asbestos.

A short-term exposure limit is one that addresses the average exposure over a 15-30 minute period of maximum exposure during a single work shift. A ceiling limit is one that may not be exceeded for any time, and is applied to irritants and other materials that have immediate effects.